My brother and myself experimented with direct drilling back in the 70,s using the Bettinson and MF drills which were no comparison to the John Deere which we have used later, it is brilliant.
What beat us in the seventies( we carried on the experiment for six years on about 10 acres) were blackgrass and grass weeds and compaction.
You could beat compaction with a Bomford subsoiler, we still have it but don,t use it. Compaction and wheelings can reduce your yield and you need maximum yiield today.
In the 70,s we used gromoxome (Paraquat) for weed control which did not translocate so weed control eventually beat us.
Nowadays you would of course use roundup or glyphosphate which is much better. That was what attracted us so much to GM, it performs brilliantly. Exactly why the Americans and Canadians have gone a bundle on GM.
Good luck with your experiment, on really heavy land the equation is fairly balanced on direct drilling, you save a hell of of a lot of energy and sprays, but to survive now you need absolute maximum yield.
Good Luck,
Jack Caley